領(lǐng)學(xué)術(shù)科研之先,創(chuàng)食品科技之新
—— 中國食品雜志社
期刊集群
Effects of soy hull polysaccharide on dyslipidemia and pathoglycemia in rats induced by a high-fat-high-sucrose diet
來源:食品科學(xué)網(wǎng) 閱讀量: 271 發(fā)表時(shí)間: 2021-12-08
作者: Qian Lin, Lina Yang, Lin Han, Ziyi Wang, Mingshuo Luo, Danshi Zhu, He Liu, Xin Li, Yu Feng
關(guān)鍵詞: Soy hull polysaccharide, Antihyperlipidemic, Gut microbiota, Short-chain fatty acids
摘要:

The present work aimed at investigating the effects of soy hull polysaccharide (SHP) in alleviating adverse effects in rats fed a high-fat-high-sucrose diet. After SHP feeding for 4 weeks, the fasting blood glucose (FBG), serum triglyceride (TG), serum high-density lipoprotein cholesterol (HDL-C), short chain fatty acids (SCFAs), and 16S rDNA gene sequence were determined. Administration of SHP significantly decreased body fat content and TG levels, and increased water intake and HDL-C levels after 4 weeks of treatment. The antihyperglycemic effect of SHP at a dose of 400 mg/kg mb had the most significant effects among the three dosage groups. SHP notably restored the FBG in rats fed a high-fat-high-sucrose diet (P < 0.05). Furthermore, SHP at 400 mg/kg mb increased the abundance of Bacteroidetes and decreased that of Firmicutes and Actinobacteria at the phylum level. The polysaccharide treated groups had significantly higher content of total SCFAs, and the main fermentation products were acetic, propionic, n-valeric and i-valeric acids. Thus, SHP restores blood lipid levels in rats fed a high-fat-high sucrose diet through regulation of the gut microbiota.

電話: 010-87293157 地址: 北京市豐臺(tái)區(qū)洋橋70號(hào)

版權(quán)所有 @ 2023 中國食品雜志社 京公網(wǎng)安備11010602060050號(hào) 京ICP備14033398號(hào)-2

迁安市| 彭阳县| 岐山县| 定兴县| 岱山县| 肥乡县| 兰州市| 手游| 承德县| 天镇县| 阿鲁科尔沁旗| 城步| 平凉市| 海南省| 耒阳市| 河西区| 阜康市| 江门市| 逊克县| 和静县| 临颍县| 新疆| 樟树市| 辽宁省| 曲松县| 徐州市| 永兴县| 伽师县| 安新县| 高碑店市| 谢通门县| 尉犁县| 阿瓦提县| 新闻| 安吉县| 沈阳市| 西乌珠穆沁旗| 商都县| 浦江县| 沙河市| 富源县|