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A novel AgNPs/MOF substrate-based SERS sensor for high-sensitive on-site detection of wheat gluten
來源:導(dǎo)入 閱讀量: 197 發(fā)表時間: 2024-03-12
作者: Linglin Fu, Yanzhuo Du, Jinru Zhou, Huan Li, Minzi Wang, Yanbo Wang
關(guān)鍵詞: Wheat allergy; Gluten; Surface-enhanced Raman scattering; Metal-organic framework; DNA recognition
摘要:

Gluten, known as the major allergen in wheat, has gained increasing concerns in industrialized countries, resulting in an urgent need for accurate, high-sensitive, and on-site detection of wheat gluten in complex food systems. Herein, we proposed a silver nanoparticles (AgNPs)/metal-organic framework (MOF) substrate-based surface-enhanced Raman scattering (SERS) sensor for the high-sensitive on-site detection of wheat gluten. The detection occurred on the newly in-situ synthesized AgNPs/MOF-modified SERS substrate, providing an enhancement factor (EF) of 1.89 × 105. Benefitting from the signal amplification function of AgNPs/MOF and the superiority of SERS, this sensor represented high sensitivity performance and a wide detection range from 1 × 10-15 mol/L to 2 × 10-6 mol/L with a detection limit of 1.16 × 10-16 mol/L, which allowed monitoring the trace of wheat gluten in complex food system without matrix interference. This reliable sandwich SERS sensor may provide a promising platform for high-sensitive, accurate, and on-site detection of allergens in the field of food safety.

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