領(lǐng)學(xué)術(shù)科研之先,創(chuàng)食品科技之新
—— 中國(guó)食品雜志社
期刊集群
Rice bran polysaccharide ameliorates ovalbumin-induced allergy and improves gut microbiota composition
來(lái)源:導(dǎo)入 閱讀量: 2 發(fā)表時(shí)間: 2025-10-23
作者: Bingjie Chen, Yongjin Qiao, Chong Wang, Xiao Wang, Yi Zhang, Linglin Fu
關(guān)鍵詞: Rice bran polysaccharide; Food allergy; Gut microbiota
摘要:

This study is the first investigation of the effects of polysaccharide extracted from rice bran (RBP) on ovalbumin (OVA)-induced allergy and the gut microbiota, which hasn’t been reported previously. RBP in the medium-dose was found to significantly reduce the symptoms of food allergy (FA) in mice, lower the levels of histamine and allergen-specific (immunoglobulin E), and attenuate intestinal inflammation. Further studies demonstrated that RBP decreased allergy-associated responses in intestinal epithelial cells and Th2 cells while regulating Th1/Th2 differentiation to reach a dynamic equilibrium and downregulating Th2 polarization caused by allergies. Short-chain fatty acids (SCFAs) content and 16S rRNA sequencing revealed that RBP enhanced the abundance and diversity of the gut microflora and raised the content of SCFAs. These results suggest that RBP may mitigate FA by modulating the gut microbiota. This study revealed the effective use of rice bran and served as a basis for the development of innovative functional foods with anti-allergic properties.

電話(huà): 010-87293157 地址: 北京市豐臺(tái)區(qū)洋橋70號(hào)

版權(quán)所有 @ 2023 中國(guó)食品雜志社 京公網(wǎng)安備11010602060050號(hào) 京ICP備14033398號(hào)-2

镇坪县| 汉阴县| 香港| 修水县| 武安市| 无锡市| 玉林市| 鄂伦春自治旗| 巴楚县| 曲阳县| 望奎县| 平湖市| 博白县| 聊城市| 新蔡县| 晋宁县| 邵阳市| 固始县| 建宁县| 平乡县| 三江| 陇川县| 西峡县| 扎兰屯市| 乡宁县| 奈曼旗| 凤庆县| 扎鲁特旗| 无极县| 普格县| 罗定市| 池州市| 乌什县| 肥城市| 眉山市| 离岛区| 阜新市| 峨山| 灵寿县| 罗平县| 寻乌县|