領(lǐng)學(xué)術(shù)科研之先,創(chuàng)食品科技之新
—— 中國食品雜志社
期刊集群
Structural characteristics, anticoagulant and antithrombotic mechanism of a novel polysaccharide from Rosa Chinensis Flos
來源:食品科學(xué)網(wǎng) 閱讀量: 126 發(fā)表時間: 2022-10-28
作者: Xiaofeng Zhang, Zhenhua Liang, Geoffrey Ivan Neil Waterhouse, Shengjun Jiang, Dongxiao Sun-Waterhouse, Jinmei Wang, Changyang Ma, Wenyi Kang
關(guān)鍵詞: Rosa Chinensis Flos; Polysaccharide isolation; Antithrombotic activity; Intestinal flora
摘要:

This is the first report on a polysaccharide (RCJ2-Ib) isolated from Rosa Chinensis Flos. RCJ2-Ib was obtained through the extraction with water, precipitation with ethanol, separation with DEAE-52 column and purification with DEAE-Sepharose Fast Flow column and Sephadex G100 column. GC, FT-IR and NMR analyses revealed that RCJ2-Ib (3.3 kDa) was a 1,4-linked polymannuronic acid containing substantial β-D-anomers units. The anticoagulant effect of RCJ2-Ib evaluated by using rabbit ear venous blood and an acute blood stasis rat model showed that RCJ2-Ib had obvious anticoagulant activity in regulating endogenous and exogenous coagulation pathways and reducing serum thromboxane B2 and endothelin-1. In addition, RCJ2-Ib could also increase the number of Lactobacillus and Escherichia coli. As a result, RCJ2-Ib has the potential to inhibit thrombosis and maintain the intestinal environment.

電話: 010-87293157 地址: 北京市豐臺區(qū)洋橋70號

版權(quán)所有 @ 2023 中國食品雜志社 京公網(wǎng)安備11010602060050號 京ICP備14033398號-2

海盐县| 三亚市| 寿宁县| 咸丰县| 确山县| 乐亭县| 方山县| 石嘴山市| 平利县| 龙海市| 舞阳县| 奉化市| 梓潼县| 吉木萨尔县| 肥城市| 福建省| 德州市| 汕头市| 突泉县| 冕宁县| 剑阁县| 三都| 南汇区| 蚌埠市| 革吉县| 会昌县| 额尔古纳市| 怀远县| 澄迈县| 修水县| 盐城市| 广德县| 颍上县| 太原市| 子洲县| 浠水县| 思南县| 霍林郭勒市| 金溪县| 甘肃省| 藁城市|